The phosphate salt of codeine occurs as white, needle-formed crystals or white crystalline powder. Codeine phosphate is freely soluble in drinking water and slightly soluble in Liquor. The molecular body weight is 406.37. Its molecular components is C18H21NO3•H3PO4 • ½ H2O, and it's got the subsequent chemical construction.

Disposal of Unused Promethazine HCl and Codeine Phosphate Oral Remedy Suggest patients to properly get rid of unused Promethazine HCl and Codeine Phosphate Oral Remedy. Advise clients to toss the drug from the home trash next these ways. 1) Get rid of them from their original containers and blend them having an unwanted compound, including used coffee grounds or kitty litter (this will make the drug considerably less captivating to children and Animals, and unrecognizable to folks who may intentionally go throughout the trash in search of medication).

Your Health care provider could do blood assessments to check for adrenal gland complications. Connect with your healthcare service provider without delay Should you have any of those indications:

Concomitant administration of promethazine items with other respiratory depressants has an Affiliation with respiratory despair, and often Loss of life, in pediatric sufferers.

When presented concomitantly with Promethazine HCl Oral Resolution, the dose of barbiturates must be lessened by a minimum of a person-half, as well as the dose of narcotics should be minimized by one particular-quarter to one-half. Dosage need to be individualized. Extreme amounts of Promethazine HCl relative to your narcotic may well result in restlessness and motor hyperactivity while in the individual with ache; these signs and symptoms ordinarily disappear with suitable Charge of the pain.

Amplified stress within your head (amplified intracranial stress). Stay away from the usage of Promethazine Hydrochloride and Codeine Phosphate Oral Option Should you have a head damage or have been told that you've alterations during the tissue of the Mind (brain lesions) or increased tension within your head.

Sedation This product or service relieves apprehension and induces a peaceful snooze from which the affected individual is often easily aroused.

Small blood pressure level. A sudden drop in blood pressure level can transpire in some people during cure with Promethazine Hydrochloride and Codeine Phosphate Oral Answer which may possibly cause you to definitely experience dizzy, faint, lightheaded, or weak, especially when you get up (orthostatic hypotension). Your risk of having this issue could possibly be elevated if you're taking Promethazine Hydrochloride and Codeine Phosphate Oral Solution with sure other medicines that lessen blood pressure level.

Lower blood pressure. A unexpected drop in blood pressure can happen in some people all through cure with Promethazine Hydrochloride and Codeine Phosphate Oral Resolution and this may well result in you to definitely come to feel dizzy, faint, lightheaded, or weak, especially when you arise (orthostatic hypotension). Your danger of click here getting this issue can be improved if you are taking Promethazine Hydrochloride and Codeine Phosphate Oral Remedy with sure other medicines that reduced hypertension.

Due to probable for promethazine to reverse epinephrine’s vasopressor result, epinephrine should NOT be employed to deal with hypotension linked to promethazine overdose.

Postmarketing circumstances of respiratory despair, like fatalities, happen to be described with use of promethazine hydrochloride in pediatric clients lower than 2 a long time of age. A variety of bodyweight-centered doses of promethazine hydrochloride have resulted in respiratory melancholy in these patients.

Respiration issues (respiratory despair)that can cause death and opioid withdrawal can transpire if you start getting or cease having other medicines even though taking Promethazine Hydrochloride and Codeine Phosphate Oral Resolution, which includes:

The typical effective dose of Promethazine HCl Oral Remedy with the Lively therapy of nausea and vomiting in children or Older people is twenty five mg.

Caution needs to be exercised when administering Promethazine HCl Oral Resolution to pediatric people 2 years of age and more mature due to the likely for deadly respiratory depression. Respiratory depression and apnea, at times connected to Demise, are strongly connected with promethazine merchandise and are not directly connected with individualized bodyweight-primarily based dosing, which could in any other case allow Risk-free administration.